For Healthcare Professionals

Questions? Call 855-4ADYNOVATE

ADYNOVATE Proven prophylaxis + simple, twice-weekly dosing schedule =

moments their way

ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] allows patients to infuse on the same 2 days every week.1

  • Efficacy

    ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] offers proven prophylaxis with a twice-weekly dosing schedule.1

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  • Dosing & Administration

    Get information about the simple, twice-weekly dosing schedule, the BAXJECT II Hi-Flow Needleless Transfer Device, and available dosage strengths.

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  • Safety

    Learn about safety findings from the ADYNOVATE clinical trial.

    See Details
  • Dedicated Support

    Baxalta is proud to provide a variety of programs and resources for the bleeding disorders community.

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  • The Science

    Learn more about the extended terminal half-life of ADYNOVATE.1

    Explore the Science

Detailed Important Risk Information
Prescribing Information (PI)
ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] Important Information
Indication

ADYNOVATE, Antihemophilic Factor (Recombinant), PEGylated, is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older) with hemophilia A (congenital factor VIII deficiency) for:

  • On-demand treatment and control of bleeding episodes
  • Routine prophylaxis to reduce the frequency of bleeding episodes

ADYNOVATE is not indicated for the treatment of von Willebrand disease.

DETAILED IMPORTANT RISK INFORMATION


Please see ADYNOVATE full Prescribing Information.



ADVATE [Antihemophilic Factor (Recombinant)] Important Information
Indication

ADVATE is a recombinant antihemophilic factor indicated for use in children and adults with hemophilia A (congenital factor VIII deficiency) for:

  • Control and prevention of bleeding episodes.
  • Perioperative management.
  • Routine prophylaxis to prevent or reduce the frequency of bleeding episodes.

ADVATE is not indicated for the treatment of von Willebrand disease.

DETAILED IMPORTANT RISK INFORMATION

Neutralizing Antibodies
Neutralizing antibodies (inhibitors) have been reported following administration of ADVATE predominantly in previously untreated patients (PUPs) and previously minimally treated patients (MTPs). Monitor all patients for the development of factor VIII inhibitors by appropriate clinical observation and laboratory testing. If expected plasma factor VIII activity levels are not attained, or if bleeding is not controlled with an expected dose, perform an assay that measures factor VIII inhibitor concentration.

Please see ADVATE full Prescribing Information.